Xxx coli

Xxx coli-52Xxx coli-61Xxx coli-11

This modeling method finds the limits of cellular, biochemical and systemic functions, thereby identifying all allowable solutions.

Searches within the allowable solution space can identify solutions of interest, for example a solution that maximizes a particular objective.

Each gene included in the model is associated with at least one reaction.

Examples of different types of associations are shown, where the top layer is the gene locus, the second layer is the translated peptide, the third layer is the functional protein and the bottom layer is the reaction (shown as its corresponding abbreviation listed in the additional data file).

Synthesis of proteins with multiple disulfide bonds is challenging due to formation of non-native disulfide bonds.

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